In the face of crucibles, hardships could become excuses for failure instead of achievements. Yet why do these experiences often make leaders instead of break them? As part of the MIT Leadership Video Series, Deborah Ancona, faculty director of the MIT Leadership Center, sits down with Una Ryan, current managing director of Golden Seeds, an angel investing group focused on women-led companies, and former president and CEO of Diagnostics for All, to explore this question and learn how Una turned her own misfortunes into missions.